Emergency crews are responding to a significant roof fire at a building in the heart of Manhattan’s Soho neighborhood.

Massive flames and thick smoke were reported late Tuesday evening, initially described as coming from the area near Broadway and Broome Street.

The fire was first reported by a 911 caller, prompting police to arrive on the scene and confirm a heavy smoke condition.

Firefighters were dispatched to what was initially reported as 451 Broome Street but later confirmed to be 487 Broadway, which houses a TJ Maxx store on the ground level.

As firefighters arrived, the blaze was found to be concentrated on the roof, with flames spreading quickly.

The fire was elevated to a second alarm, bringing additional resources and personnel to the scene to combat the growing inferno.

Adding to the urgency, fire crews on the scene reported that a baby was inside the smoke-filled penthouse of the building. Rescue operations are ongoing as firefighters work to locate and safely evacuate anyone trapped inside.

This is a developing story, and authorities are expected to release more information as they assess the situation.

Residents and visitors in the area are advised to avoid the vicinity while emergency crews work to bring the fire under control.