Don Keller, an officer with the Greenwood Police Department, was killed Monday night following a violent crash on East Cambridge Avenue in Greenwood, according to officials.

Authorities said the deadly collision occurred between North Ames Street and North Hospital Street in a residential area of the city.

Witnesses at the scene described what appeared to be a high-speed pursuit involving a vehicle carrying at least three young occupants.

According to residents, the chase reportedly began on a side street connected to East Cambridge Avenue before escalating toward the intersection near New Street.

As the fleeing vehicle approached North Hospital Street, witnesses said another law enforcement vehicle entered the area and a head-on collision occurred near the intersection of East Cambridge Avenue and New Street.

The impact left the police vehicle heavily damaged, with airbags deployed throughout the patrol unit. A blue truck was also reportedly involved in the crash.

Debris from the collision, including vehicle parts and personal items such as tennis shoes, was scattered across the roadway as emergency crews rushed to the scene.

Multiple law enforcement agencies, including the South Carolina Highway Patrol, Greenwood County deputies, and Greenwood police officers, remained at the scene late Monday night as investigators worked to reconstruct the crash and gather evidence.

Witnesses reported seeing at least one person airlifted from the scene for emergency medical treatment, while two others were reportedly taken into custody in handcuffs. Authorities have not yet publicly released the conditions or identities of the additional people involved.

The South Carolina Highway Patrol is leading the investigation into the fatal crash.

Residents in the neighborhood said the crash unfolded in an area where families and children are commonly outside during the evening hours, leaving many shaken by the tragedy.

Following news of Keller’s death, condolences poured in from across South Carolina, including a statement from Tim Scott, who honored the fallen officer’s service and sacrifice.

“South Carolinians mourn the loss of an Upstate officer who dedicated their life to keeping our community safe and made the ultimate sacrifice doing so,” Scott said. “To their loved ones and fellow officers, our hearts are with you in this time of grief. My deepest condolences.”

Authorities have not yet released additional details regarding the circumstances surrounding the pursuit or whether criminal charges are expected as the investigation continues.